Monmouth Plantation is located at the intersection of John Quitman Parkway and Melrose Avenue in historic Natchez, Mississippi. Natchez is approximately 92 miles north of Baton Rouge via Highway 61.

From Baton Rouge: Take Hwy 61N to Natchez. After entering the city limits, go through 4 traffic lights. At the fifth light, turn left on Melrose-Montebello Parkway. Turn left on John Quitman Parkway. Monmouth is on the left.

From Jackson, Mississippi: Take I-55 S to Hwy 84 to Hwy 61 toward Natchez. Turn left on Junkir Street and left on John Quitman Parkway. Monmouth is on the left.

Baton Rouge Metropolitan Airport (BTR) is approximately ninety miles from the inn.