21c Museum Hotel Louisville by MGallery

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The hotel is situated within Louisville’s historic Museum Row neighborhood. This terrific enclave is home to a variety of the city’s museums, including the Kentucky Science Center, the Muhammad Ali Center, and the Louisville Slugger Museum. Guests can visit more local landmarks further into town, like Churchill Downs—the home of the Kentucky Derby. Louisville Int’l Airport: 8.5 miles, 15 minutes.

Nearest Airport

Louisville International Airport (SDF): 5 miles, 12 minutes

Hotel Address

700 W. Main Street, Louisville

Kentucky, United States 40202

Historic Hotels of America Recommended Points of Interest

  • Cherokee Park

    Cherokee Park

    Spend some time outdoors at this amazing public park.

  • Churchill Downs

    Churchill Downs

    Discover this iconic racecourse just moments away.

  • Kentucky Derby Museum

    Kentucky Derby Museum

    Explore the heritage of the Kentucky Derby at the Kentucky Derby Museum.

  • Louisville Palace Theatre

    Louisville Palace Theatre

    Attend a theatrical performance at the Louisville Palace Theatre.

  • Louisville Slugger Museum & Factory

    Louisville Slugger Museum & Factory

    Experience the culture of American baseball at the Louisville Slugger Museum & Factory.

  • Louisville Zoo

    Louisville Zoo

    Discover the wide variety of animals at the Louisville Zoo.

  • Mellwood Art And Entertainment Center

    Mellwood Art and Entertainment Center

    Explore the Mellwood Art and Entertainment Center.

  • Muhammad Ali Center

    Muhammad Ali Center

    Experience the life of the legendary boxer at the Muhammad Ali Center.

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